Roles of Akt and SGK1 in the Regulation of Renal Tubular Transport

Figure 5

Roles of Akt and SGK1 in transport regulation at each nephron segment: Akt and SGK1 modify renal tubular transport by activating or inhibiting several transporters at each nephron segment. Targets and functions of the kinases in proximal tubules, distal convoluted tubules, and cortical collecting ducts are shown in (a), (b), and (c), respectively.

(a)

(b)

(c)