BioMed Research International / 2015 / Article / Tab 2

Research Article

Acute and Chronic Toxicity, Cytochrome P450 Enzyme Inhibition, and hERG Channel Blockade Studies with a Polyherbal, Ayurvedic Formulation for Inflammation

Table 2

(a) Hematology in rats treated with BV-9238 (male) for chronic toxicity studies. (b) White blood cell differential count in %. (c) Hematology in rats treated with BV-9238 (female) for chronic toxicity studies. (d) White blood cell differential count in %.
(a)

Dose Group IGroup IIGroup IIIGroup IV
Vehicle control1 g/kg/d2 g/kg/d2 g/kg/d

Hb (g%)
PCV (%)
RBC × 106/cm
WBC total × 103/cm
Clotting time (sec.)

(b)

Dose Group IGroup IIGroup IIIGroup IV
Vehicle control1 g/kg/d2 g/kg/d2 g/kg/d

Neutrophils
Lymphocytes
Eosinophils
Monocytes

(c)

Dose Group IGroup IIGroup IIIGroup IV
Vehicle control1 g/kg/d2 g/kg/d2 g/kg/d

Hb (g%)
PCV (%)
RBC × 106/cm
WBC total × 103/cm
Clotting time (sec.)

(d)

Dose Group IGroup IIGroup IIIGroup IV
Vehicle control1 g/kg/d2 g/kg/d2 g/kg/d

Neutrophils
Lymphocytes
Eosinophils
Monocytes

Values are expressed as mean and standard deviation. Values are nonsignificant when compared with Group I (control) animals.

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