Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model
Clearance of bacteria from the bloodstream was impaired in mice. Tissues were harvested and cultured on day 38 (3 days after secondary infection) to measure bacterial load. (a) Average CFU/mL ± SE for blood samples and average CFU/g ± SE for liver, spleen, kidney, and lymph node samples, shown on a log scale ( per group). (b) The same data as in (a), but shown as the fold difference of compared to wild type, to emphasize the 60-fold increase in blood bacterial load.