Research Article

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model

Figure 5

Clearance of bacteria from the bloodstream was impaired in mice. Tissues were harvested and cultured on day 38 (3 days after secondary infection) to measure bacterial load. (a) Average CFU/mL ± SE for blood samples and average CFU/g ± SE for liver, spleen, kidney, and lymph node samples, shown on a log scale ( per group). (b) The same data as in (a), but shown as the fold difference of compared to wild type, to emphasize the 60-fold increase in blood bacterial load.