Effects of Chronic REM Sleep Restriction on D₁ Receptor and Related Signal Pathways in Rat Prefrontal Cortex

Figure 2

(a) The results of DA content in the two groups (). Compared to that of the TC group, the DA content in the CSR group was notably reduced. (b) Effects of CSR on the expressions of some genes in PFC (). CSR notably reduced the Drd1a in the CSR rats (B1). The expressions of Creb1, Acdy5, Prkaca, Darpp32, Erk1, and Erk2 in PFC showed no significant differences between the CSR and TC groups (B2–B7). TC: treatment control; CSR: chronic sleep restriction. ^∗, and ^∗∗.