Long-Term Clinical Outcome after Treatment for High-Grade Cervical Lesions: A Retrospective Monoinstitutional Cohort Study

Table 1

Principal characteristics of the 760 cases included in the study.

		%
Histological diagnosis at baseline
CIN2	415	54.6
CIN3/in situ carcinoma	330	43.4
Microinvasive carcinoma	15	2.0
Colposcopic diagnosis at baseline
Negative	87	11.4
G1 (abnormal grade 1)	378	49.7
G2 (abnormal grade 2)	279	36.7
Suspected invasive carcinoma	1	0.1
Missing	15	2.0
Squamocolumnar junction location
Type 1 (visible, ectocervical)	532	70.0
Type 2 (visible, endocervical)	158	20.8
Type 3 (nonvisible, in endocervix)	52	6.8
Missing	18	2.4
Treatment
LEEP	684	90.0
Conization	76	10.0
Margins status of the excised specimens
Negative	506	66.6
Positive	126	16.6
Not assessable	20	2.6
Missing	108	14.2
HPV test at first follow-up
Negative	350	48.5
HPV 16	34	4.7
Other high-risk HPV	33	4.6
Low-risk HPV	89	12.2
Not performed	215	29.8
Residual^* lesions
CIN2	17	2.2
CIN3	15	2.0
Microinvasive carcinoma	3	0.4
Invasive carcinoma	1	0.1
VAIN2	2	0.3
VAIN3	1	0.1
Recurrent^** lesions
CIN2	17	2.2
CIN3	5	0.7
VAIN2	5	0.7
VAIN3	1	0.1

Residual: lesions detected at first follow-up.
^**Recurrent: lesions detected after one or more negative follow-up visits.