Shaped 3D Singular Spectrum Analysis for Quantifying Gene Expression, with Application to the Early Zebrafish Embryo

Figure 1

Zebrafish data [4] and the 3D-SSA approach: original nucleus position data for the spherical-cap gene expression region, with simulated intensity values (a schematic two-exponential pattern, with noise) represented by the color map; colors are given in the topographic scale, where the blue color corresponds to small values, when brown/red colors correspond to large values of intensity.

(a) Initial data on a sphere

(b) Results of data reconstruction: the denoised pattern on a sphere