The Effect of Esmolol on Tissue Perfusion and Clinical Prognosis of Patients with Severe Sepsis: A Prospective Cohort Study

Table 4

The effect of esmolol on tissue perfusion indicators in patients with severe sepsis.

(Time, H)	Esmolol group ()	Control group ()
Mean ± standard deviation
Lac, mmol/L
Base value	8.98 ± 3.09	9.74 ± 4.05	−1.301	0.195
24	6.62 ± 2.43	6.82 ± 2.43	−0.522	0.603
48	3.87 ± 1.89	3.10 ± 1.9	2.493	0.014
72	2.32 ± 0.98	2.41 ± 1.07	−0.534	0.594
P(va)CO2, mmHg
Base value	9.54 ± 3.89	10.12 ± 3.52	−0.947	0.345
24	6.71 ± 3.29	7.26 ± 3.34	−1.019	0.310
48	5.11 ± 2.10	5.94 ± 2.38	−2.285	0.024
72	2.73 ± 1.08	3.06 ± 1.73	−1.415	0.160
ScvO2
Base value	0.7711 ± 0.0566	0.7762 ± 0.0592	−0.537	0.592
24	0.8000 ± 0.0529	0.7679 ± 0.0510	3.798	0.000
48	0.7932 ± 0.0441	0.7657 ± 0.0569	3.318	0.001
72	0.7957 ± 0.0362	0.7636 ± 0.0551	4.227	0.000