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BioMed Research International
Volume 2016 (2016), Article ID 1048320, 7 pages
Research Article

Antibacterial Properties of Calcium Fluoride-Based Composite Materials: In Vitro Study

1Department of General Dentistry, Medical University of Lodz, Lodz, Poland
2Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Lodz, Poland
3Department of Conservative Dentistry, Medical University of Lodz, Lodz, Poland

Received 10 June 2016; Revised 3 October 2016; Accepted 10 November 2016

Academic Editor: Gilberto Sammartino

Copyright © 2016 Monika Łukomska-Szymańska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of the study was to evaluate antibacterial activity of composite materials modified with calcium fluoride against cariogenic bacteria S. mutans and L. acidophilus. One commercially available conventional light-curing composite material containing fluoride ions (F2) and two commercially available flowable light-curing composite materials (Flow Art and X-Flow) modified with 1.5, 2.5, and 5.0 wt% anhydrous calcium fluoride addition were used in the study. Composite material samples were incubated in 0.95% NaCl at 35°C for 3 days; then dilution series of S. mutans and L. acidophilus strains were made from the eluates. Bacteria dilutions were cultivated on media afterwards. Colony-forming unit per 1 mL of solution (CFU/mL) was calculated. Composite materials modified with calcium fluoride highly reduced () bacteria growth compared to commercially available composite materials containing fluoride compounds. The greatest reduction in bacteria growth was observed for composite materials modified with 1.5% wt. CaF2. All three tested composite materials showed statistically greater antibacterial activity against L. acidophilus than against S. mutans.