Dietary Flavonoid Hyperoside Induces Apoptosis of Activated Human LX-2 Hepatic Stellate Cell by Suppressing Canonical NF-κB Signaling

Figure 1

Structure of hyperoside and its inhibitory proliferation effect on LX-2 cells. (a) Chemical structure of hyperoside. (b) Effect of hyperoside on the growth of LX-2 cell lines for 24 h. (c) Effect of hyperoside on the growth of LX-2 cell lines for 48 h. Cell proliferation was analyzed using MTT assay. Cells were treated with different concentration of hyperoside (0, 0.125, 0.25, 0.5, 1.0, and 2.0 mM/L). Results represent the mean ± SEM from three independent experiments ( compared with the control group, ).

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