Aberrant Expression Profile of Long Noncoding RNA in Human Sinonasal Squamous Cell Carcinoma by Microarray Analysis

Figure 1

(a) Brief microarray results of lncRNAs. Expression levels of 78,243 lncRNAs were assessed in 6 pairs of SSCC tissues and paired adjacent noncancerous sinonasal tissues using Agilent Human lncRNA  K microarrays. Compared with paired adjacent noncancerous tissues, 3146 lncRNAs (4.02%) had significant changes in expression levels (fold change >2, ). A total of 874 lncRNAs were excluded due to low expression levels. A total of 3146 lncRNAs were then identified from the screen, with 1174 upregulated and 1098 downregulated. (b) Brief microarray results of mRNAs. Expression levels of 32,776 mRNAs were assessed in 6 pairs of SSCC tissues and paired adjacent noncancerous sinonasal tissues using Agilent Human lncRNA  K microarrays. Compared with paired adjacent noncancerous tissues, 2208 mRNAs (6.73%) had significant changes in expression levels (fold change >2, ). A total of 284 mRNAs were precluded due to low expression levels. A total of 2208 lncRNAs were then identified from the screen, with 821 upregulated and 1103 downregulated.

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