Intramyocardial Injection of siRNAs Can Efficiently Establish Myocardial Tissue-Specific Renalase Knockdown Mouse Model

Figure 4

There is no difference of fluorescent density between the sham and I/R operation groups. 24 h after intramyocardial injection of Cy3-labeled cholesterol-conjugated-specific siRNAs (3 mM, 20 μL), sham and I/R operations were performed; myocardial tissues were subjected to frozen section and fluorescent imaging. The fluorescent density of each group was analyzed. Scale bar represents 200 μm. Data are plotted as the mean ± SD from five independent experiments. Bars indicate the standard deviation of the mean.