Research Article
G-1639A but Not C1173T VKORC1 Gene Polymorphism Is Related to Ischemic Stroke and Its Various Risk Factors in Ukrainian Population
Table 7
Clinical characteristics of IS patients with different VKORC1 C1173T genotypes.
| | Parameter | C/C | C/T | T/T | Total | |
| | 63 | 74 | 33 | 170 | — | | BMI, kg/m2 | 28.2 ± 5.0 | 28.3 ± 3.8 | 28.0 ± 4.0 | 28.2 ± 4.3 | 0.961 | | Systolic BP, mmHg | 166.6 ± 28.9 | 167.6 ± 32.3 | 166.4 ± 22.6 | 167.0 ± 29.2 | 0.973 | | Diastolic BP, mmHg | 94.1 ± 13.9 | 96.6 ± 18.3 | 95.0 ± 11.7 | 95.4 ± 15.6 | 0.657 | | Total cholesterol, mmol/L | 5.09 ± 1.6 | 4.98 ± 1.4 | 5.13 ± 1.6 | 5.05 ± 1.5 | 0.862 | | HDL-cholesterol, mmol/L | 1.05 ± 0.3 | 1.01 ± 0.3 | 1.00 ± 0.3 | 1.02 ± 0.3 | 0.670 | | LDL-cholesterol, mmol/L | 3.25 ± 1.5 | 3.22 ± 1.4 | 3.35 ± 1.5 | 3.26 ± 1.4 | 0.910 | | Triglyceride, mmol/L | 1.74 ± 0.8 | 1.66 ± 0.8 | 1.72 ± 0.9 | 1.70 ± 0.8 | 0.820 | | Prothrombin time, s | 9.56 ± 2.0 | 9.61 ± 2.1 | 8.99 ± 1.9 | 9.48 ± 2.0 | 0.313 | | Thrombin time, s | 16.59 ± 3.5 | 16.73 ± 3.6 | 16.00 ± 3.6 | 16.54 ± 3.6 | 0.616 | | Fibrinogen, g/L | 3.85 ± 1.2 | 3.85 ± 1.3 | 4.26 ± 1.1 | 3.93 ± 1.2 | 0.227 | | Fasting glucose, mmol/L | 6.02 ± 1.6 | 5.85 ± 1.4 | 5.90 ± 1.7 | 5.92 ± 1.5 | 0.795 |
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: number of subjects; HDL: high density lipoprotein; LDL: low density lipoprotein.
= 59 for C/C genotype, for C/T genotype, and for T/T genotype.
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