Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis

Figure 1

Ratio of Mgmt, Gsta1, and Gstp1 ((a), (b), and (c), resp.)/to the ribosomal housekeeping gene Rplp1 mRNA in wt rats in basal conditions, DMH-treated wt rats, Pirc rats in basal conditions, and DMH-treated Pirc rats. Values are expressed as percent over the basal wt mean values. (d) FRAP determination in wt, DMH-treated wt, Pirc, and DMH-treated Pirc rats. # and §: significant effect of DMH treatment or genotype, respectively, by two-way ANOVA analysis. : significantly different compared to the corresponding basal condition by t-test analysis ().

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