Research Article
Exposure to p,p′-DDE Induces Morphological Changes and Activation of the PKCα-p38-C/EBPβ Pathway in Human Promyelocytic HL-60 Cells
Figure 1
p,p′-DDE exposure does not affect cell viability and proliferation. (a) Percentage of viable cells and (b) proliferation of cells exposed to 0.019, 0.19, and 1.9 μg/mL of p,p′-DDE as evaluated by MTT assay and [3H]-thymidine incorporation, respectively. Data from three independent experiments are expressed as the mean ± standard error mean (SEM). indicates differences from the control group; and indicate differences from 1.9 μg/mL of p,p′-DDE at 24 h. Data were analysed using a one-way ANOVA followed by Dunnett’s post hoc or Bonferroni’s multiple comparison tests. indicates differences from the control group.
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