Influence of APOE Genotype on Alzheimer’s Disease CSF Biomarkers in a Spanish Population

Table 3

Influence of age on CSF AD variables.

CSF variables	Age	Number of; patients	Mean ± SD	Significance level	Adjusted significance level
Aβ protein; (pg/mL)	≥75; <75	16; 40	858.63 ± 457.41; 1146.1 ± 444.34	0.03	0.06
T-tau protein; (pg/mL)	≥75; <75	16; 40	381.75 ± 172.46; 283.18 ± 218.34	0.11	0.38
			Median (25–75)
p-tau protein; (pg/mL)	≥75; <75	16; 40	59 (52.0–88.68); 40 (42.1–60.15)	0.01	0.21
Ratio; T-tau/Aβ	≥75; <75	16; 40	0.42 (0.35–0.74); 0.16 (0.21–0.45)	0.007	0.26
Ratio; p-tau/Aβ	≥75; <75	16; 40	0.07 (0.05–0.15); 0.03 (0.04–0.07)	0.004	0.09

Student’s -test. Mann-Whitney test.