Influence of APOE Genotype on Alzheimer’s Disease CSF Biomarkers in a Spanish Population

Table 5

Influence of APOE genotype and age over the progression to AD.

	Frequency of progression to AD	Crude odds ratio (95% CI)	Adjusted odds ratio (95% CI)
Genotype
ε2	10.0% (1/10)	1	1
ε3	12.9% (4/31)	1.3 (0.1–13.5)	0.9 (0.08–10.5)
ε4	60.0% (9/15)	13.5 (1.3–136.0)	4.7 (0.3–69.9)
Age
≥75	43.8% (7/16)	3.7 (1.1–13.2)	2.9 (0.6–13.4)
<75	17.5% (7/40)	1	1