Association between the Achievement of Target Range CKD-MBD Markers and Mortality in Prevalent Hemodialysis Patients in Taiwan by Using the Kidney Disease: Improving Global Outcomes Clinical Guidelines
Table 6
Odds ratio of all-cause and CV mortality by achievement of KDIGO clinical guideline.
OR (95% CI)
Model 1
Model 2
Model 3
All-cause
All
1.00
1.00
1.00
Ca + P
1.52 (1.05~2.21)
0.02
1.85 (1.16~2.95)
0.009
1.66 (1.01~2.73)
0.04
Ca + iPTH
0.96 (0.60~1.52)
0.84
1.39 (0.81~2.39)
0.23
1.43 (0.77~2.68)
0.25
P + iPTH
1.07 (0.46~2.52)
0.87
1.50 (0.59~3.78)
0.39
1.32 (0.46~3.77)
0.60
Ca
1.85 (1.14~3.00)
0.01
4.02 (2.12~7.63)
<0.001
3.16 (1.52~6.59)
0.002
P
3.95 (1.65~9.46)
0.002
4.54 (1.61~12.8)
0.004
3.55 (1.05~12.0)
0.04
iPTH
2.51 (1.08~5.83)
0.03
4.69 (1.56~14.1)
0.005
4.70 (1.44~15.4)
0.01
None
2.19 (1.06~4.52)
0.03
1.99 (0.77~5.13)
0.15
3.91 (1.00~15.3)
0.05
CV
All
1.00
1.00
1.00
Ca + P
1.30 (0.60~2.85)
0.50
1.30 (0.49~3.41)
0.59
1.39 (0.51~3.77)
0.51
Ca + iPTH
1.75 (0.78~3.92)
0.17
2.58 (1.04~6.39)
0.04
2.96 (1.08~8.13)
0.03
P + iPTH
0.77 (0.10~5.96)
0.80
1.40 (0.17~11.9)
0.75
1.01 (0.11~9.66)
0.99
Ca
1.39 (0.50~3.89)
0.52
4.13 (1.32~13.0)
0.01
4.35 (1.20~15.9)
0.02
P
NA
NA
NA
iPTH
3.71 (1.01~13.6)
0.04
3.47 (0.62~19.4)
0.15
2.40 (0.40~14.3)
0.33
None
1.58 (0.35~7.14)
0.55
0.82 (0.10~6.86)
0.85
1.43 (0.12~16.9)
0.77
Logistic regression model: Model 1: unadjusted. Model 2: adjusted for age, sex, hemodialysis vintage, etiology of renal failure, EPO, vitamin-D analogs, antihypertensive agent, iron use, and parathyroidectomy. Model 3: model 2 + baseline laboratory results (albumin, hemoglobin, cholesterol, triglyceride, glucose (fasting), ferritin, Ca, P, iPTH, potassium, uric acid, urea, and cardiac-thoracic ratio).
