The CYBA Gene 49A>G Polymorphism (rs7195830) Is Associated with Hypertension in Patients with Coronary Artery Disease

Table 1

Biochemical and clinical characteristics of analyzed groups.

Characteristic	CAD; N = 242	BD; N = 239	Statistics results
	Mean ± SD	Mean ± SD	P
Age (years)	44.79 ± 5.94	43.62 ± 6.46	0.92
TC (mmol/L)	5.81 ± 1.34	5.06 ± 1.21	<0.000
LDL-C (mmol/L)	4.03 ± 1.20	3.11 ± 1.17	<0.000
HDL-C (mmol/L)	1.11 ± 0.37	1.44 ± 0.56	<0.000
TG (mmol/L)	1.89 ± 0.97	1.39 ± 0.73	<0.000
BMI	27.24 ± 4.16	26.08 ± 3.83	0.001
	% (n)	% (n)	OR (95% CI), P univariate analysis
Male gender	70.6 (173)	71.0 (174)	0.98 (0.65–1.47), 0.92
TC ≥ 5 mmol/L	70.0 (168)	47.9 (117)	2.53 (1.71–3.75), <0.000
LDL ≥ 3 mmol/L	77.6 (184)	50.4 (123)	3.42 (2.26–5.17), <0.000
HDL-C ≤ 1 mmol/L ♂	48.1 (114)	24.6 (60)	2.84 (1.90–4.27), <0.000
≤ 1.2 mmol/L ♀
TG ≥ 1.7 mmol/L	53.3 (128)	27.0 (66)	3.14 (2.11–4.68), <0.000
BMI ≥ 25	70.7 (152)	56.1 (129)	1.89 (1.25–2.85), 0.001
Cigarette smoking	60.3 (146)	27.8 (68)	3.94 (2.64–5.87), <0.000
Hypertension	58.2 (137)	2.9 (7)	46.00 (19.94–111.51), <0.000
Diabetes mellitus	8.7 (21)	0 (0)	2.08 (1.89–2.29), <0.000^1
Familial history of CAD	36.0 (87)	0 (0)	2.54 (2.25–2.87), <0.000^1

Risk ratio values (95% CI), univariate analysis.
CAD: coronary artery disease patients, BD: blood donors, and OR: odds ratio.