Research Article
Rapid Identification of Potential Drugs for Diabetic Nephropathy Using Whole-Genome Expression Profiles of Glomeruli
Table 3
Top 20 drug perturbations with high negative connectivity scores.
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Instance: a treatment and control pair and the list of probe sets ordered by their extent of differential expression between this treatment and control pair; instance ID: the ID uniquely identifying each instance; CMAP name: the name given to a perturbagen; dose: perturbagen dose; cell: cell line; up: the up score, a value between +1 and −1 representing the absolute enrichment of an up tag list in a given instance; down: the down score, a value between +1 and −1 representing the absolute enrichment of a down tag list in a given instance; score: the connectivity score, a combination of the up score and the down score. A high negative connectivity score indicates that the corresponding perturbagen reversed the expression of the query signature. |