Proapoptotic Role of Potassium Ions in Liver Cells

Figure 2

Potassium ions affected cell cycle of liver cells. L02 () and HepG2 () cells were added to 6-well plates cocultured with different concentrations of potassium ions for 48 hrs. Then the effects of potassium ions on cell cycle of L02 and HepG2 were determined by flow cytometry. (a) In L02 cells, potassium ions induced significantly decrease of S phase and increase of G2 phase in a dose-dependent manner (). (b) In HepG2 cells, potassium ions induced significantly decrease of S phase and increase of G1 phase in a dose-dependent manner (). All data are represented as mean ± SEM. , .

(a)

(b)