Quantitative Myocardial Perfusion with Dynamic Contrast-Enhanced Imaging in MRI and CT: Theoretical Models and Current Implementation

Figure 3

Illustration of contrast agent (blue dots) distribution in the tissue: is the plasma volume within the intravascular space, is the extravascular extracellular space, is the perfusion flow within the intravascular space, and PS is the permeability-surface exchange rate between and . Another parameter, the extraction fraction (), denotes the proportion of contrast agent exchanged to the extravascular extracellular space.