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BioMed Research International
Volume 2016, Article ID 1752854, 12 pages
http://dx.doi.org/10.1155/2016/1752854
Review Article

Roles and Clinical Applications of OPG and TRAIL as Biomarkers in Cardiovascular Disease

Department of Medical, Surgical and Health Sciences, University of Trieste, Cattinara Teaching Hospital, Strada di Fiume, 34149 Trieste, Italy

Received 29 January 2016; Revised 28 March 2016; Accepted 5 April 2016

Academic Editor: Laurent Metzinger

Copyright © 2016 Stella Bernardi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [13 citations]

The following is the list of published articles that have cited the current article.

  • Dominique Heymann, and Marie-Françoise Heymann, “Osteoprotegerin,” Encyclopedia of Signaling Molecules, pp. 1–7, 2016. View at Publisher · View at Google Scholar
  • Barbara Toffoli, Bruno Fabris, Giacomo Bartelloni, Fleur Bossi, and Stella Bernardi, “Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System,” Mediators of Inflammation, vol. 2016, pp. 1–7, 2016. View at Publisher · View at Google Scholar
  • Ahmed M. Abu El-Asrar, Ajmal Ahmad, Kaiser Alam, Emilie Bittoun, Mohammad Mairaj Siddiquei, Ghulam Mohammad, Ahmed Mousa, Gert De Hertogh, and Ghislain Opdenakker, “Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy,” Ocular Immunology and Inflammation, pp. 1–13, 2017. View at Publisher · View at Google Scholar
  • Lena Tschiderer, Johann Willeit, Georg Schett, Stefan Kiechl, and Peter Willeit, “Osteoprotegerin concentration and risk of cardiovascular outcomes in nine general population studies: Literature-based meta-analysis involving 26,442 participants,” Plos One, vol. 12, no. 8, pp. e0183910, 2017. View at Publisher · View at Google Scholar
  • Stella Bernardi, Barbara Toffoli, Fleur Bossi, Riccardo Candido, Elisabetta Stenner, Renzo Carretta, Fabio Barbone, and Bruno Fabris, “Circulating osteoprotegerin is associated with chronic kidney disease in hypertensive patients,” BMC Nephrology, vol. 18, no. 1, 2017. View at Publisher · View at Google Scholar
  • Stella Bernardi, Fleur Bossi, Barbara Toffoli, Fabiola Giudici, Alessandra Bramante, Giulia Furlanis, Elisabetta Stenner, Paola Secchiero, Giorgio Zauli, Renzo Carretta, and Bruno Fabris, “Association between thyroid hormones and TRAIL,” Clinical Biochemistry, 2017. View at Publisher · View at Google Scholar
  • Mable Misha Singh, Ravindra Kumar, Satyendra Tewari, and Sarita Agarwal, “Investigation of OPG/RANK/RANKL Genes as a Genetic Marker for Cardiac abnormalities in Thalassemia Major Patients,” Annals of Human Genetics, 2017. View at Publisher · View at Google Scholar
  • Dominique Heymann, and Marie-Françoise Heymann, “Osteoprotegerin,” Encyclopedia of Signaling Molecules, pp. 3687–3693, 2017. View at Publisher · View at Google Scholar
  • Yen-Cheng Chen, Bang-Gee Hsu, Ching-Chun Ho, Chung-Jen Lee, and Ming-Che Lee, “Elevated serum osteoprotegerin may predict peripheral arterial disease after kidney transplantation: a single-center prospective cross-sectional study in Taiwan,” PeerJ, vol. 5, pp. e3847, 2017. View at Publisher · View at Google Scholar
  • Veronica Tisato, Paola Secchiero, Gloria Bonaccorsi, Carlo Bergamini, Pantaleo Greco, Giorgio Zauli, and Carlo Cervellati, “Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women,” Mediators of Inflammation, vol. 2017, pp. 1–8, 2017. View at Publisher · View at Google Scholar
  • Yunfei Wang, Mengmeng Liu, Shijian Deng, Xin Sui, Linlin Fan, and Qi Zhang, “Osteoprotegerin deficiency causes morphological and quantitative damage in epithelial rests of Malassez,” Journal of Molecular Histology, 2018. View at Publisher · View at Google Scholar
  • Jining Yang, Daoyuan Si, Yanan Zhao, Chengyan He, and Ping Yang, “S-amlodipine improves endothelial dysfunction via the RANK/RANKL/OPG system by regulating microRNA-155 in hypertension,” Biomedicine & Pharmacotherapy, vol. 114, pp. 108799, 2019. View at Publisher · View at Google Scholar
  • Stella Bernardi, Rebecca Voltan, Erika Rimondi, Elisabetta Melloni, Daniela Milani, Carlo Cervellati, Donato Gemmati, Claudio Celeghini, Paola Secchiero, Giorgio Zauli, and Veronica Tisato, “TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?,” Clinical Science, vol. 133, no. 10, pp. 1145–1166, 2019. View at Publisher · View at Google Scholar