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BioMed Research International
Volume 2016, Article ID 1758501, 5 pages
http://dx.doi.org/10.1155/2016/1758501
Research Article

Serum Procalcitonin and Procalcitonin Clearance as a Prognostic Biomarker in Patients with Severe Sepsis and Septic Shock

1Department of Medicine, Taichung Tzu Chi Hospital, the Buddhist Medical Foundation, Taichung 42743, Taiwan
2Division of Emergency Medicine, Department of Pediatrics, Changhua Christian Hospital, Changhua 500, Taiwan
3School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan
4School of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan
5Department of Laboratory Medicine, Taichung Tzu Chi Hospital, the Buddhist Medical Foundation, Taichung 42743, Taiwan
6Laboratory of Epidemiology and Biostatistics, Changhua Christian Hospital, Changhua 500, Taiwan
7School of Post-Baccalaureate Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan
8Department of Hematology-Oncology, Children’s Hospital, China Medical University Hospital, China Medical University, Taichung 404, Taiwan
9Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan 333, Taiwan
10College of Medicine, Chang Gung University, Taoyuan 333, Taiwan

Received 23 January 2016; Revised 1 March 2016; Accepted 2 March 2016

Academic Editor: Kurt G. Naber

Copyright © 2016 Min-Yi Huang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. M. Levy, M. P. Fink, J. C. Marshall et al., “2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference,” Intensive Care Medicine, vol. 29, no. 4, pp. 530–538, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. M. S. Rangel-Frausto, D. Pittet, M. Costigan, T. Hwang, C. S. Davis, and R. P. Wenzel, “The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study,” The Journal of the American Medical Association, vol. 273, no. 2, pp. 117–123, 1995. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Guan, Z. Lin, and H. Lue, “Dynamic change of procalcitonin, rather than concentration itself, is predictive of survival in septic shock patients when beyond 10 ng/mL,” Shock, vol. 36, no. 6, pp. 570–574, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. J. C. Ruiz-Rodríguez, J. Caballero, A. Ruiz-Sanmartin et al., “Usefulness of procalcitonin clearance as a prognostic biomarker in septic shock. A prospective pilot study,” Medicina Intensiva, vol. 36, no. 7, pp. 475–480, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. H. L. Sun, K. H. Wu, S. M. Chen et al., “Role of procalcitonin in predicting dilating vesicoureteral reflux in young children hospitalized with a first febrile urinary tract infection,” The Pediatric Infectious Disease Journal, vol. 32, no. 9, pp. e348–e354, 2013. View at Publisher · View at Google Scholar
  6. B. Suberviola, A. Castellanos-Ortega, A. González-Castro, L. A. García-Astudillo, and B. Fernández-Miret, “Prognostic value of procalcitonin, C-reactive protein and leukocytes in septic shock,” Medicina Intensiva, vol. 36, no. 3, pp. 177–184, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Rhodes, G. Phillips, R. Beale et al., “The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study),” Intensive Care Medicine, vol. 41, no. 9, pp. 1620–1628, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. R. G. Gupta, S. M. Hartigan, M. G. Kashiouris, C. N. Sessler, and G. M. L. Bearman, “Early goal-directed resuscitation of patients with septic shock: current evidence and future directions,” Critical Care, vol. 19, article 286, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. R. P. Dellinger, M. M. Levy, A. Rhodes et al., “Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012,” Critical Care Medicine, vol. 41, no. 2, pp. 580–637, 2013. View at Publisher · View at Google Scholar
  10. G. S. Martin, D. M. Mannino, S. Eaton, and M. Moss, “The epidemiology of sepsis in the United States from 1979 through 2000,” The New England Journal of Medicine, vol. 348, no. 16, pp. 1546–1554, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. C. Brun-Buisson, F. Doyon, J. Carlet et al., “Incidence, risk factors, and outcome of severe sepsis and septic shock in adults: a multicenter prospective study in intensive care units,” Journal of the American Medical Association, vol. 274, no. 12, pp. 968–974, 1995. View at Publisher · View at Google Scholar · View at Scopus
  12. A. C. Heffner, J. M. Horton, M. R. Marchick, and A. E. Jones, “Etiology of illness in patients with severe sepsis admitted to the hospital from the emergency department,” Clinical Infectious Diseases, vol. 50, no. 6, pp. 814–820, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Grozdanovski, Z. Milenkovic, I. Demiri, K. Spasovska, M. Cvetanovska, and V. Kirova-Urosevic, “Early prognosis in patients with community-acquired severe sepsis and septic shock: analysis of 184 consecutive cases,” Prilozi, vol. 33, no. 2, pp. 105–116, 2012. View at Google Scholar
  14. D. W. Bates, K. Sands, E. Miller et al., “Predicting bacteremia in patients with sepsis syndrome,” Journal of Infectious Diseases, vol. 176, no. 6, pp. 1538–1551, 1997. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Artero, R. Zaragoza, J. J. Camarena, S. Sancho, R. González, and J. M. Nogueira, “Prognostic factors of mortality in patients with community-acquired bloodstream infection with severe sepsis and septic shock,” Journal of Critical Care, vol. 25, no. 2, pp. 276–281, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. Y.-X. Chen and C.-S. Li, “Arterial lactate improves the prognostic performance of severity score systems in septic patients in the ED,” American Journal of Emergency Medicine, vol. 32, no. 9, pp. 982–986, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Innocenti, S. Bianchi, E. Guerrini et al., “Prognostic scores for early stratification of septic patients admitted to an emergency department-high dependency unit,” European Journal of Emergency Medicine, vol. 21, no. 4, pp. 254–259, 2014. View at Publisher · View at Google Scholar · View at Scopus