Nicotinamide Mononucleotide Adenylyl Transferase 2: A Promising Diagnostic and Therapeutic Target for Colorectal Cancer

Table 4

Univariate and multivariate Cox regression analyses of prognostic factors for 5-year survival.

Parameters	Univariate	HR (95% CI)	Multivariate
Gender
Male
Female
Age
≥65
<65
Morphology
Ulcerative type		3.105 (1.165–8.273)
Polypoid type
Histological type
Adenocarcinoma
Mucous carcinoma
Differentiation
Well
Middle and poor
Average diameter
≥3		2.993 (1.480–6.054)
<3
Depth of invasion
T1 + T2
T3 + T4
Lymph metastasis
N0
N1 + N2
TNM stage
I + II		4.508 (2.303–8.822)
III + IV
NMNAT2 expression
Negative
Positive
p53 expression
Negative
Positive