Effects of Exercise Interventions and Physical Activity Behavior on Cancer Related Cognitive Impairments: A Systematic Review

Table 3

Human cross-sectional and observational studies.

Reference		Study design	Study population	Status of therapy	Duration	Parameters	Correlations
Crowgey et al., 2014 [45]	51; 37 chemotherapy; 14 healthy	Cross-sectional study	Breast cancer	After chemotherapy, during hormone therapy		() Self-reported physical activity (Leisure Score Index); () Cardiovascular fitness (VO2 peak); () Central nervous system vital signs software	LSI, visual memory
Hartman et al., 2015 [46]	136	Cross-sectional study	Breast cancer	After chemotherapy, during hormone therapy		() Physical activity; () Cognitive function; (a) Memory; (b) Executive function; (c) Visual areal processing; (d) Attention; (e) Information processing	Physical activity, executive function; Physical activity, attention
Marinac et al., 2015 [47]	136	Cross-sectional study	Breast cancer	After chemotherapy, during hormone therapy	1 week (time of activity tracking)	() Physical activity (low, moderate, inactive); () Cognitive function; (a) Information processing; (b) Memory; (c) Executive function	MKA,; information processing
Fitzpatrick et al., 2012 [48]	15; 8 during chemotherapy; 7 after chemotherapy	Cohort study	Prostate and breast cancer	During and after chemotherapy	6 weeks	() Cognitive function; (a) Montreal Cognitive Assessment; (b) Healthy brain questionnaire; () MET	MoCA,; MET

MPA: Moderate Physical Activity; PA: physical activity; LSI: Leisure Score Index; MET: Metabolic Equivalent of Task; fMRI: functional Magnetic Resonance Imaging; MoCA: Montreal Cognitive Assessment.