Expression Profiling of Genes Related to Endothelial Cells Biology in Patients with Type 2 Diabetes and Patients with Prediabetes

Table 4

Functional gene grouping.

Angiogenesis	ANGPT1, CCL2, CCL5, CX3CL1, EDN1, EDNRA, ENG, F3, FASLG, FGF1, FLT1, FN1, IL1B, IL6, ITGA5, ITGAV, ITGB1, ITGB3, KDR, KIT, MMP2, MMP9, NOS3, PF4, PGF, PLAU, PTGS2, SERPINE1, SPHK1, TEK, THBS1, TYMP, VEGFA.
Vasoconstriction & vasodilation	ACE, AGT, ALOX5, APOE, CALCA, CX3CL1, EDN1, EDN2, EDNRA, F2R, ICAM1, NOS3, PTGIS, PTGS2, SOD1.
Inflammatory response	ACE, AGT, ALOX5, APOE, CALCA, CCL2, CCL5, CX3CL1, EDNRA, F2R, F3, FN1, IL1B, IL6, PTGS2, SELE, SPHK1, TGFB1, THBS1, TNF.
Apoptosis	ANXA5, BAX, BCL2, BCL2L1, CASP1, CASP3, CCL2, CCL5, CFLAR, CX3CL1, EDN1, EDNRA, FAS, FASLG, IL1B, IL3, IL6, IL7, PF4, PTK2, SPHK1, TEK, THBS1, TNF, TNFSF10.
Cell adhesion	ADAM17, AGT, BCL2, CALCA, CDH5, COL18A1, CX3CL1, ENG, FGF1, FN1, ICAM1, IL1B, ITGA5, ITGAV, ITGB1, ITGB3, KDR, PECAM1, PLAU, PLG, PTK2, SELE, SELL, SELPLG, SERPINE1, TGFB1, THBS1, TNF, VEGFA, VWF.
Coagulation	ANXA5, EDN1, F2R, F3, FN1, MMP1, PECAM1, PF4, PLAT, PLAU, PLG, PROCR, PTK2, SELL, SELPLG, SERPINE1, TEK, TFPI, THBD, THBS1, TIMP1, VWF.
Platelet activation	APOE, CX3CL1, F2R, FN1, IL11, IL6, ITGB3, NOS3, PECAM1, PF4, PLG, SERPINE1, SOD1, TGFB1, THBD, THBS1, TIMP1, VEGFA, VWF.