Sunlight Effects on Immune System: Is There Something Else in addition to UV-Induced Immunosuppression?

Table 1

Summary of irradiation protocols producing UV-induced immunosuppression. The experimental design of all the papers cited in the table included the irradiation before the sensitization stage of the immune responses. CHS: contact hypersensitivity; DTH: delayed type hypersensitivity; Oxa: oxazolone; DNFB: 2,4-dinitrofluorobenzene; Ova: ovalbumin.

Authors	UV source	UV dose employed	MED represented	Mice strain	Type of reaction (antigen)
Reeve et al. [43]	UVA/UVB	3 × 4500 mJ/cm^2 (UVA); 3 × 252 mJ/cm^2 (UVB)	1 MED	C57BL/6	CHS (Oxa)
Majewski et al. [44]	UVR	4 × 150 mJ/cm^2	Not expressed	C57BL/6	CHS (DNFB)
Wang et al. [45]	UVB	3 × 45 mJ/cm^2	Not expressed	C57BL/6	CHS (DNFB); OT1 T-cell proliferation (Ova)
Schwarz et al. [46]	UVB	4 × 150 mJ/cm^2	Not expressed	C57BL/6	CHS (DNFB)
Gorman et al. [47]	65% UVB	400 and 800 mJ/cm^2	>1 MED	Balb/c and C57BL/6	CHS (DNFB)
Zhang et al. [48]	45% UVB	750 mJ/cm^2	Not expressed	C57BL/6	CHS (DNFB)
Guéniche et al. [49]	UVB + UVA	Not expressed	2.5 MED	SKH:HR1	CHS (DNFB)
Shreedhar et al. [9]	65% UVB	1500 mJ/cm^2	Not expressed	C3H/HeN	DTH (alloantigen)
Li et al. [50]	UVB	200 mJ/cm^2	Not expressed	C57BL/6	CHS (DNFB)
Rana et al. [51]	UVB	3 × 150 mJ/cm^2	0.5 MED	C57BL/6	DTH (Ova)
Dixon et al. [52]	UVB and UVA	3 × 400 mJ/cm^2 (UVB)	3 MED	SKH:HR1	CHS (Oxa)