Research Article

Evaluation of Bone Metabolism in Critically Ill Patients Using CTx and PINP

Table 2

Values for BTMs obtained from controls versus patients over time (weeks) of ICU stay.

ParameterControls (n = 14)Baseline (n = 28)1st (n = 28)2nd (n = 19)3rd (n = 11)4th (n = 8)5th (n = 7)

-CTX, ng/mL0.47 (0.34–0.63)0,95 (0,37–1,49)1,54 (0,99–1,90)1,64 (1,34–2,15)1,2 (0,83–2,05)0,96 (0,68–1,59)1.15 (0,79–1,30)
P1NP, ng/mL45.5 (33.7–62.1)12,75 (9,53–20,56)20,6 (13,7–28,5)27,4 (16,1–66,5)52,8 (41,1–82,8)204,3 (50,1–327,8)281,1 (56,8–460,7)
iPTH, pg/mL49.5 (42.3–60.4)175,4 (110,5–258,9)102,5 (53,2–202,5)88,4 (29,8–159)96,5 (42,8–126,5)63,7 (29,8–110,9)66,1 (20,2–71,3)
25-OH VitD24.1 (22.9–27.1)3,4 (2,0–6,1)4,9 (2,0–9,8)4,9 (2,0–9,1)3,8 (2,0–8,1)6,6 (3,6–8,4)5,1 (2,0–6,8)

ng/mL values are expressed as median (±IQR).