Wnt-β-Catenin Signaling Promotes the Maturation of Mast Cells

Figure 3

Activation of Wnt canonical signaling in mast cells by Wnt5a. (a) BMMCs were cultured with Wnt5a (50 ng/mL), and then the expression of β-catenin in these cells was detected in Western blot analysis. Representative results from one of three independent experiments performed are shown. (b) Gene expression levels of Axin2 and TCF were measured by quantitative RT-PCR. Gene expression levels in the control were taken as 1.0. All data represent the means ± SD (). .

(a)

(b)