Heteroreceptors Modulating CGRP Release at Neurovascular Junction: Potential Therapeutic Implications on Some Vascular-Related Diseases

Table 2

Physiological functions of CGRP in humans and rodents.

Function	Species	Tissue [reference]
Vasodilatation	Rat	Vascular bed [14, 22]
		Kidney [23]
	Human	Cerebral arteries [24]
		Middle meningeal artery [25]
		Artery segments from thymus [26]
Inotropic positive effects	Human	Myocardium [27]
	Rat	Ventricular cardiomyocytes [28]
Ingest inhibition	Rat	In vivo [29]
Antiproliferative	Rat	Cellular culture (smooth muscle) [30]
Suppression of aldosterone release	Rat	Zona glomerulosa cells [31]
Thermal hyperalgesia	Mouse	Skin [32]
		Spinal cord [32]