Syntaxin 5 Overexpression and <i>β</i>-Amyloid 1–42 Accumulation in Endoplasmic Reticulum of Hippocampal Cells in Rat Brain Induced by Ozone Exposure

<div>Triple IF to detect beta-amyloid 1–42 in the ER. Five micrometer-thick brain tissue sections form the hippocampi of the control group (CTRL) and the rats exposed to O<sub>3</sub> (0.025 ppm) for 3 months (3 M) are shown. Goat anti-GRP78 was used as ER marker. Rabbit anti-<i>β</i>A42 is shown in green and GRP78 in red. DAPI staining and merge between the red, green, and blue channels are shown (MERGE). The arrows indicate the intracellular <i>β</i>A42 deposition and colocalization in ER. There was no <i>β</i>A42 detection at 7, 15, 30, and 60 days of treatment (data not shown).</div>

BioMed Research International

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Figure 1

Figure 1: Syntaxin 5 Overexpression and <i>β</i>-Amyloid 1–42 Accumulation in Endoplasmic Reticulum of Hippocampal Cells in Rat Brain Induced by Ozone Exposure 

Figure 1 | Syntaxin 5 Overexpression and β-Amyloid 1–42 Accumulation in Endoplasmic Reticulum of Hippocampal Cells in Rat Brain Induced by Ozone Exposure 