Review Article
Potential Roles of Amiloride-Sensitive Sodium Channels in Cancer Development
Figure 1
Contribution of ENaC/ASIC mediating Na+ current to cell volume in cancer cell development. ENaC/ASIC mediating Na+ influx promoted the proliferation, migration, and invasion of cancer cell, compared to blockage of this Na+ influx inducing cell cycle arrest and apoptosis of cancer cell.