Diagnostic Accuracy of Robot-Guided, Software Based Transperineal MRI/TRUS Fusion Biopsy of the Prostate in a High Risk Population of Previously Biopsy Negative Men

Table 4

Detection rate of prostate cancer in peripheral versus central target biopsy.

	Any cancer			Significant cancer
	Peripheral% ()	Central% ()	value	Peripheral% ()	Central% ()	value
Overall	39.0 (29/75)	22.0 (13/60)	0.0223	32.0 (24/75)	15.0 (9/60)	0.0342
PiRADS score
5	75.0 (6/8)	100.0 (4/4)	0.32	75.0 (6/8)	75.0 (3/4)	0.99
4	56.0 (14/25)	25.0 (4/16)	0.052	44.0 (11/25)	19.0 (3/16)	0.10
3	27.0 (6/22)	12.0 (4/34)	0.14	23.0 (5/22)	6.0 (2/34)	0.065
2	9.0 (1/1)	0.0 (0/5)	—	9.0 (1/1)	0.0 (0/5)	—
Unclassified	22.0 (2/9)	100.0 (1/1)	—	11.0 (1/9)	100.0 (1/1)	—

PiRADS: Prostate imaging Reporting and Detection System.
: prostate cancer with any Gleason grade; : prostate cancer with Gleason grade ≥ 4.