Research Article
HIV-1 Epidemiology, Genetic Diversity, and Primary Drug Resistance in the Tyumen Oblast, Russia
Table 2
Detection rate and range of mutations in the pol gene in the examined HIV-1 variants that influence the sensitivity to virus reproduction inhibitors.
| HIV-1 mutations associated with DR mutation (rate, %) | Resistance to PIs, | Resistance to NRTIs, | Resistance to NNRTIs, | Resistance to IIs, |
| K20R (12.5), T74S (12.5), L10V.I (11.1), K20I (5.6), L33F (2.8), A71I (1.4) | A62V (8.3), V118I (6.9), T69S (4.2) | E138A (4.2), G190E (1.4), Y181C (1.4), N108I (1.4), V90I (1.4) | L74I (94.1), T66I (1.5), T97A (1.5), E157Q (1.5), T97A (1.5) |
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: the number of analyzed sequences.
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