Research Article

HIV-1 Epidemiology, Genetic Diversity, and Primary Drug Resistance in the Tyumen Oblast, Russia

Table 2

Detection rate and range of mutations in the pol gene in the examined HIV-1 variants that influence the sensitivity to virus reproduction inhibitors.

⁢HIV-1 mutations associated with DR mutation (rate, %)
Resistance to PIs, Resistance to NRTIs, Resistance to NNRTIs, Resistance to IIs,

K20R (12.5), T74S (12.5), L10V.I (11.1), K20I (5.6), L33F (2.8), A71I (1.4)A62V (8.3), V118I (6.9), T69S (4.2)E138A (4.2), G190E (1.4), Y181C (1.4), N108I (1.4), V90I (1.4)L74I (94.1), T66I (1.5), T97A (1.5), E157Q (1.5), T97A (1.5)

: the number of analyzed sequences.