Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation

Figure 3

Outcome of Western blot (). (a) The representative bands of Western blot, (b) optical density of IL-1β, and (c) optical density of NLRP3. Values are mean ± SD. N: normal group; M: model group; 3.125 μM Ber, 6.25 μM Ber, 12.5 μM Ber, and 25 μM Ber: berberine group (Ber) of different concentrations. NLRP3: domain present in neuronal apoptosis inhibitor protein major histocompatibility complex class II transactivator, leucine rich repeat, and pyrin domains-containing protein 3.

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