Beneficial Effect of Short Pretransplant Period of Hypothermic Pulsatile Perfusion of the Warm-Ischemic Kidney after Cold Storage: Experimental Study

Figure 1

Renal injury is attenuated by the use of pulsatile hypothermic machine perfusion after cold storage. (a) Representative images of renal pathology (hematoxylin-eosin, magnifications ×20 and ×40). Note the signs of inflammation (asterisks) and hyaline casts (arrows) in the kidneys subjected only to cold storage compared with those that also received the perfusion by the use of pulsatile machine. The bar in the cortex or medulla pictures represents 100 μm while in glomerulus images it represents 50 μm. (b) Semiquantitative renal injury score. Results are expressed as mean ± SEM, –12 animals per group. versus control group; versus cold storage group. CS: cold storage; HMP: hypothermic machine perfusion; AT: autotransplant.

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