Menoprogen, a TCM Herbal Formula for Menopause, Increases Endogenous E₂ in an Aged Rat Model of Menopause by Reducing Ovarian Granulosa Cell Apoptosis

Table 1

Effects of Menoprogen and estradiol valerate (Progynova) on ovarian and uterine weight of aged rats ().

Rat group	Ovarian coefficient (10^−1)	Uterine coefficient (10^−1)
Normal control	2.79 ± 0.38	2.06 ± 0.55
NAM	2.15 ± 0.46	1.47 ± 0.23
Low-dose	2.70 ± 0.34	1.72 ± 0.25
Middle-dose	2.56 ± 0.37	1.99 ± 0.23
High-dose	2.63 ± 0.37	1.97 ± 0.48
Progynova	2.51 ± 0.58	1.94 ± 0.53

⁢ < 0.05, < 0.01, and < 0.001 versus NAM group.
Organ coefficient = organ wet weight/body weight × 100%.