Research Article
Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis
Figure 3
QC4 destroyed gastric cancer cell membrane integrity. (a) SGC-7901 and MGC80-3 were incubated with QC4 for indicated time at 10 μg/mL, and the culture supernatants were subjected to LDH leakage analysis. (b) PI uptake assay was performed after QC4 administration. QC4 increased PI uptake in SGC-7901 and MGC80-3 cells after QC4 administration for indicated time at 10 μg/mL ( for QC4 treatment compared with the DMSO treated control group in SGC-7901; for QC4 treatment compared with the DMSO treated control group in MGC80-3).
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