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BioMed Research International
Volume 2016, Article ID 2694060, 8 pages
Review Article

Strengths, Pitfalls, and Lessons from Longitudinal Childhood Asthma Cohorts of Children Followed Up into Adult Life

1Respiratory and Sleep Medicine, Women’s and Children’s Hospital, King William Road, North Adelaide, SA 5006, Australia
2Robinson Research Institute, University of Adelaide, SA 5005, Australia

Received 11 April 2016; Revised 26 August 2016; Accepted 21 September 2016

Academic Editor: Denis Caillaud

Copyright © 2016 Andrew Tai. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Asthma is a common problem worldwide and longitudinal studies of children followed up into adult life enable the assessment of clinical outcomes, examine the pattern of lung function outcomes, and importantly provide insight into aetiology and prognosis for patients with asthma. The aim of this review is to examine the major childhood asthma cohort studies which have continued into adult life, describing the strengths and weaknesses and the lessons that can be learnt regarding pathophysiology and potential future directions for research.