DASAF: An R Package for Deep Sequencing-Based Detection of Fetal Autosomal Abnormalities from Maternal Cell-Free DNA

Figure 1

Workflow of the R package DASAF. The DASAF workflow consists of two main parts: (a) mapping reads statistics and (b) autosomal aneuploidy prediction. The results from (a) are used to calculate the risk score using any of the four methods implemented in (b). STDZ: standard -score; GCCZ: GC correction -score; IRZ: internal reference -score; and SCAZ: subchromosome abnormalities -score.