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BioMed Research International
Volume 2016 (2016), Article ID 2849476, 5 pages
Research Article

Feasibility and Safety of Absorbable Knotless Wound Closure Device in Laparoscopic Myomectomy

1Department of Obstetrics and Gynecology, Taipei City Hospital, Zhongxiao Branch, Taipei 11556, Taiwan
2Department of Obstetrics and Gynecology, Taipei City Hospital, Renai Branch, Taipei 10629, Taiwan
3National Defense Medical Center, Taipei 114, Taiwan

Received 15 February 2016; Revised 9 May 2016; Accepted 22 May 2016

Academic Editor: Andrea Tinelli

Copyright © 2016 Chying-Chyuan Chan and Ching-Yu Lee. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. Myomectomy has been performed through laparoscopy. Suturing is known as rate-limiting step in laparoscopic myomectomy. The present study was aimed at comparing the clinical outcomes of absorbable knotless wound closure device with the results of conventional suturing. Methods. This prospective study included 62 women who underwent laparoscopic myomectomy at Taipei City Hospital, Zhongxiao Branch, from January 2010 through to August 2012. The patients were randomized into two groups according to suturing materials, the knotless group and the 2-0 Vicryl suture group. Patient demographics, overall operative time, and intraoperative blood loss were compared between two groups. Results. Demographic characteristics and laboratory variables before surgery were comparable. Operative time was significantly shorter in knotless group compared with that in 2-0 Vicryl suture group ( versus minutes; ). The results revealed a significant difference in intraoperative blood loss between two groups (knotless versus 2-0 Vicryl: versus ). Use of absorbable knotless wound closure device was associated with greater hemostasis compared with that of 2-0 Vicryl. During a 2-year follow-up period, 12 patients (46.2%) from the group with absorbable knotless wound closure device and 14 patients (38.9%) from 2-0 Vicryl suture group became pregnant. Conclusion. Closure of myometrium using absorbable knotless wound closure device after laparoscopic myomectomy resulted in a shorter operative time and less blood loss.