The Expression of NOX4 in Smooth Muscles of Small Airway Correlates with the Disease Severity of COPD

Table 1

Demographics of patients with COPD and non-COPD control subjects; data was presented as mean ± SD.

Demographics	Non-COPD cohorts	Patients with COPD
		Mild	Moderate	Severe
Subjects	19	16	14	6	NS	NS
Age (s)					0.33	0.803
Gender
Male	10	12	9	6	NS	NS
Female	9	4	5	0	NS	NS
Smoking status and cigarette consumption
Never smoking	11	6	5	1	NS	NS
Ex-smoking	1	3	3	3	NS	NS
Current smoking	7	7	6	2	NS	NS
Pack-years					1.97	0.130
Pulmonary functions
FEV1% pred					61.81	0.000
FEV1					23.93	0.000
FVC					5.19	0.003
FEV1/FVC%					97.07	0.000

Data was presented as mean ± SD. NS: no statistical difference; FEV1: forced expiratory volume in one second; FVC: forced vital capacity. value is the homogeneity of variance between two groups. values were given as COPD versus non-COPD groups.