Decreased Cytotoxicity of Peripheral and Peritoneal Natural Killer Cell in Endometriosis

Table 1

Change of the immunoregulatory factors in the NK cell cytotoxicity.

Decreased cytotoxic activity	Increased inhibitory activity
Cytotoxic function	Inflammatory cytokines
Granzyme B, perforin, TRAIL, CD107a	IL-6, IL-8, IL-1b, IFN-γ, TNF-α
Cell-activating receptors	Noninflammatory cytokines
NKp46, NKp44, NKG2D, CD16 (cell surface marker)	CXCL8, CCL-2 (MCP-1), CCL5 (RANTES)
CD69 (markers of activation)	Antigen
	HLA-G, HLA-E, HLA-I
	Inhibitory receptors
	ITIM-KIRs, KIR2DL1, NKB1, EB6, I-CAM
	Apoptosis
	FasL (CD95)