Table 1: Genotype and allele frequencies of the three selected polymorphisms and neuroblastoma susceptibility in a Chinese population.

GenotypeCases ()Controls ()Crude OR (95% CI)Adjusted OR (95% CI)

rs2228001 (HWE = 0.948)
 AA99 (39.13)218 (41.05)1.001.00
 AC118 (46.64)245 (46.14)1.06 (0.77–1.47)0.7221.05 (0.76–1.45)0.769
 CC36 (14.23)68 (12.81)1.17 (0.73–1.86)0.5211.15 (0.72–1.84)0.555
 Additive0.8071.08 (0.86–1.34)0.5201.07 (0.86–1.33)0.563
 Dominant154 (60.87)313 (58.95)0.6081.08 (0.80–1.47)0.6081.07 (0.79–1.46)0.656
 Recessive217 (85.77)463 (87.19)0.5831.13 (0.73–1.75)0.5831.12 (0.73–1.74)0.604
rs2228000 (HWE = 0.988)
 CC111 (43.87)205 (38.61)1.001.00
 CT108 (42.69)250 (47.08)0.80 (0.58–1.10)0.1700.80 (0.58–1.10)0.166
 TT34 (13.44)76 (14.31)0.83 (0.52–1.32)0.4220.84 (0.52–1.33)0.453
 Additive0.3680.88 (0.71–1.09)0.2440.88 (0.71–1.10)0.257
 Dominant142 (56.13)326 (61.39)0.1600.80 (0.59–1.09)0.1600.81 (0.59–1.09)0.162
 Recessive219 (86.56)455 (85.69)0.7420.93 (0.60–1.44)0.7420.94 (0.61–1.46)0.785
rs2229090 (HWE = 0.994)
 GG99 (39.13)191 (35.97)1.001.00
 GC105 (41.50)255 (48.02)0.79 (0.57–1.11)0.1750.79 (0.57–1.10)0.169
 CC49 (19.37)85 (16.01)1.11 (0.73–1.71)0.6261.11 (0.73–1.71)0.622
 Additive0.2041.00 (0.81–1.24)0.9711.00 (0.81–1.24)0.972
 Dominant154 (60.87)340 (64.03)0.3920.87 (0.64–1.19)0.3920.87 (0.64–1.19)0.384
 Recessive204 (80.63)446 (83.99)0.2431.26 (0.85–1.86)0.2431.26 (0.86–1.87)0.237

test for genotype distributions between neuroblastoma cases and cancer-free controls.
Adjusted for age and gender.