Research Article

Phytochemical Screening and Antinociceptive and Antidiarrheal Activities of Hydromethanol and Petroleum Benzene Extract of Microcos paniculata Barks

Table 3

Effect of standard, HMPB, and PBMPB in acetic acid induced writhing test.

GroupDoseNumber of writhing processesInhibition (%)

Control10 mL/kg36.20 ± 1.500.00 ± 0.00
DS100 mg/kg4.40 ± 0.4087.68 ± 1.36
HMPB 200 mg/kg17.00 ± 0.3252.75 ± 1.95
HMPB400 mg/kg9.40 ± 0.5173.98 ± 1.24
PBMPB200 mg/kg20.20 ± 0.3743.94 ± 1.72
PBMPB400 mg/kg13.20 ± 0.3763.13 ± 2.51

Values of the number of writhing processes are presented as mean ± standard error. mice in each group. ⁢, versus control (Dunnett’s -test); , versus DS 100 mg/kg; , versus HMPB 200 mg/kg; , versus HMPB 400 mg/kg; , versus PBMPB 200 mg/kg; , versus PBMPB 400 mg/kg (pairwise comparison by post hoc Tukey’s HSD test).