Phytochemical Screening and Antinociceptive and Antidiarrheal Activities of Hydromethanol and Petroleum Benzene Extract of Microcos paniculata Barks

Table 6

Effect of standard, HMPB, and PBMPB in castor oil-induced diarrheal test.

Group	Dose	Number of diarrheal feces	% of inhibition of diarrhea
Control	10 mL/kg	9.80 ± 0.37	0.00 ± 0.00
Loperamide HCl	3 mg/kg	1.40 ± 0.24	85.74 ± 2.37
HMPB	200 mg/kg	5.80 ± 0.37	40.65 ± 3.82
HMPB	400 mg/kg	3.60 ± 0.24	62.95 ± 3.23
PBMPB	200 mg/kg	8.40 ± 0.24	13.68 ± 4.65
PBMPB	400 mg/kg	6.00 ± 0.32	38.24 ± 4.39

Values are presented as mean ± standard error. mice in each group. ⁢, versus control (Dunnett’s -test); , versus Loperamide HCl 3 mg/kg; , versus HMPB 200 mg/kg; , versus HMPB 400 mg/kg; , versus PBMPB 200 mg/kg; , versus PBMPB 400 mg/kg (pairwise comparison by post hoc Tukey’s HSD test).