Phytochemical Screening and Antinociceptive and Antidiarrheal Activities of Hydromethanol and Petroleum Benzene Extract of Microcos paniculata Barks

Table 7

Effect of standard, HMPB, and PBMPB in MgSO₄ induced diarrheal test.

Group	Dose	Number of diarrheal feces	% of inhibition of diarrhea
Control	10 mL/kg	7.80 ± 0.37	0.00 ± 0.00
Loperamide HCl	3 mg/kg	1.80 ± 0.20	76.98 ± 2.40
HMPB	200 mg/kg	3.60 ± 0.24	52.98 ± 4.96
HMPB	400 mg/kg	2.80 ± 0.20	63.69 ± 3.35
PBMPB	200 mg/kg	3.60 ± 0.24	53.61 ± 3.35
PBMPB	400 mg/kg	2.40 ± 0.40	68.13 ± 6.13

Values are presented as mean ± standard error. mice in each group. ⁢, versus control (Dunnett’s -test); , versus Loperamide HCl 3 mg/kg; , versus HMPB 200 mg/kg; , versus PBMPB 200 mg/kg (pairwise comparison by post hoc Tukey’s HSD test).