Research Article

Effect of Sulindac Binary System on In Vitro and In Vivo Release Profiles: An Assessment of Polymer Type and Its Ratio

Table 1

Yield and drug content of SDC solid dispersions and physical mixtures at different ratios.

Binary mixtureFormula numberRatioYield (%)Drug content (%)

SDC : PVP 40000
Solid dispersion
SDV11 : 1
SDV31 : 3
SDV51 : 5

SDC : PEG 6000
Solid dispersion
SDE11 : 1
SDE31 : 3
SDE51 : 5

SDC : PVP 40000
Physical mixture
PMV11 : 1
PMV31 : 3
SDV51 : 5

SDC : PEG 6000
Physical mixture
PME11 : 1
PME31 : 3
PME51 : 5

Mean ± SD; .