Research Article
Effect of Sulindac Binary System on In Vitro and In Vivo Release Profiles: An Assessment of Polymer Type and Its Ratio
Table 1
Yield and drug content of SDC solid dispersions and physical mixtures at different ratios.
| Binary mixture | Formula number | Ratio | Yield (%) | Drug content (%) |
| SDC : PVP 40000 Solid dispersion | SDV1 | 1 : 1 | | | SDV3 | 1 : 3 | | | SDV5 | 1 : 5 | | |
| SDC : PEG 6000 Solid dispersion | SDE1 | 1 : 1 | | | SDE3 | 1 : 3 | | | SDE5 | 1 : 5 | | |
| SDC : PVP 40000 Physical mixture | PMV1 | 1 : 1 | | | PMV3 | 1 : 3 | | | SDV5 | 1 : 5 | | |
| SDC : PEG 6000 Physical mixture | PME1 | 1 : 1 | | | PME3 | 1 : 3 | | | PME5 | 1 : 5 | | |
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Mean ± SD; .
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