Treating Diabetes Mellitus: Pharmacophore Based Designing of Potential Drugs from Gymnema sylvestre against Insulin Receptor Protein

Figure 3

New designed analogues of Conduritol A (a), Conduritol B tetraacetate (b), Conduritol C cis-epoxide (c), and Conduritol D (d). To increase their binding affinity, analogues have been generated by adding benzene, Br⁻, , and into their 2D structures, respectively.

(a)

(b)

(c)

(d)