RF-Phos: A Novel General Phosphorylation Site Prediction Tool Based on Random Forest

Table 7

Scoring metrics using an independent test dataset.

Methods	Residue = S
	Sen (%)	Sp (%)	MCC
NetPhosK	80.13	38.79	0.10
GPS 2.1	94.79	28.62	0.14
NetPhos	76.55	54.20	0.16
PHOSFER	74.59	65.51	0.22
Musite	55.70	87.39	0.31
PhosphoSVM	63.84	81.76	0.29
RF-Phos	72.00	70.00	0.41
Methods	Residue = T
	Sen (%)	Sp (%)	MCC
NetPhosK	69.12	50.82	0.06
GPS 2.1	95.59	20.84	0.07
NetPhos	54.41	77.43	0.12
PHOSFER	77.94	64.77	0.14
Musite	48.53	93.55	0.26
PhosphoSVM	70.59	78.16	0.19
RF-Phos	79.00	80.00	0.50
Methods	Residue = Y
	Sen (%)	Sp (%)	MCC
NetPhosK	25.49	83.23	0.04
GPS 2.1	98.04	21.42	0.09
NetPhos	64.71	67.50	0.13
PHOSFER	62.75	59.29	0.08
Musite	47.06	88.77	0.20
PhosphoSVM	82.35	64.18	0.18
RF-Phos	61.00	62.00	0.29